Association between immune Mediated inflammatory Disease and COVID-19: A Review

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Ajeet Mandal
Nidhi Tiwari
Vinod Jamadar

Abstract

COVID-19 outbreak has affected the individuals globally and the individuals with co-morbidities such as diabetes, hypertension, aged individuals with habits such as smoking and Patient with Immune Mediated inflammation (IMI) diseases were considered at the population at higher risk COVID-19 infection and severe progression of the infection. This IMI disease consists of inflammatory bowel disease, connective tissue disease, psoriasis, inflammatory arthritis. Various drug therapies are used for such IMI diseases which include glucocorticoids, cytokine inhibitor, and interlukins which is considered to lower the risk of infection spread. Where as in this review we conclude that the use of glucocorticoids seems to worsen the  condition by increase the rate of infection spread  and requiring hospitalization, while on other hand the used of cytokine inhibitors and individuals taking methtrexate showed  a positive result owing to a good recovers and reduction in the morbidity and mortality 

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1.
Association between immune Mediated inflammatory Disease and COVID-19: A Review. JPD [Internet]. 2026 Feb. 28 [cited 2026 Feb. 28];2(1):26-3. Available from: https://journalofphysiotherapydirectories.com/index.php/index_php/article/view/24

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